Glucosamine is produced naturally in the body, yet there are no major food sources of this substance. Glucosamine is a major structural component within joint tissue and is the starting point of the synthesis of several important macromolecules including glycoproteins, glycolipids and glycosaminoglycans. These macromolecules can be found in the synovial fluid, cartilage, tendons, ligaments and muscles. Chondroitin also occurs naturally in the body and is a major component of cartilage; the tough connective tissue within joints. This formula also provides synergystic nutrients including vitamin C which contributes to normal collagen formation for the normal function of bones and cartilage, as well as manganese which contributes to the maintenance of normal bones and the formation of connective tissue.