Botanical names: Capsicum annuum, Capsicum frutescens
Some athletes say that cayenne
Topical preparations (containing the active ingredient capsaicin) have been reported to be mildly to moderately effective in clinical settings. The United States Food and Drug Administration approved capsaicin for use as a topical pain reliever in 1995. The Commission E (an expert committee established by the German government to evaluate the safety and efficacy of herbs and herb combinations sold in Germany) has also approved topical capsaicin use in adults and children for painful muscle spasms of the shoulder arm and spine.
Capsaicin ointment, applied four times daily over painful joints in the upper or lower limbs, reduces pain caused by osteoarthritis,1 and a plaster containing capsaicin applied to the low back for several hours per day provided relief from chronic low back pain in one study.2 Other uses of cayenne or capsaicin for sports and fitness have not been studied.
Besides causing a mild burning during the first few applications (or severe burning if accidentally placed in sensitive areas, such as the eyes), side effects are few with the use of capsaicin cream.3 As with anything applied to the skin, some people may have an allergic reaction to the cream, so the first application should be to a very small area of skin. Do not attempt to use capsaicin cream intra-nasally for headache treatment without professional guidance.
When consumed as food—one pepper per day for many years—cayenne may increase the risk of stomach cancer, according to one study.4 A different human study found that people who ate the most cayenne actually had lower rates of stomach cancer.5 Overall, the current scientific evidence is contradictory. Thus, the relationship between cayenne consumption and increased risk of stomach cancer remains unclear.6 Oral intake of even 1 ml of tincture three times per day can cause burning in the mouth and throat, and can cause the nose to run and eyes to water. People with ulcers, heartburn, or gastritis should use any cayenne-containing product cautiously as it may worsen their condition.
Are there any drug
interactions?
Certain medicines may interact with cayenne. Refer to
drug interactions for a list of those medicines.
Originally from South America, the cayenne plant is now used worldwide as a food and spice. Cayenne is very closely related to bell peppers, jalapeños, paprika, and other similar peppers. The fruit is used medicinally.
*Athletes and fitness advocates may claim benefits for cayenne based on their personal or professional experience. These are individual opinions and testimonials that may or may not be supported by controlled clinical studies or published scientific articles on cayenne. For more complete and detailed information, including references and safety information, see Cayenne as an herbal remedy.
1. Fusco BM, Giacovazzo M. Peppers and pain. The promise of capsaicin. Drugs 1997;53:909–14 [review].
2. Keitel W, Frerick H, Kuhn U, et al. Capsicum plaster in chronic non-specific low back pain. Arzneimittelforshung 2001;51:896–903.
3. Siften DW (ed). Physicians’ Desk Reference for Nonprescription Drugs. Montvale, NJ: Medical Economics, 1998, 790–1.
4. Lopez-Carrillo L, Avila M, Dubrow R. Chili pepper consumption and gastric cancer in Mexico: A case-control study. Amer J Epidem 1994;139:263–71.
5. Buiatti E, Palli D, Decarli A, et al. A case-control study of gastric cancer and diet in Italy. Int J Cancer 1989;44:611–6.
6. Surh YJ, Lee SS. Capsaicin in hot chili pepper: Carcinogen, co-carcinogen or anticarcinogen? Food Chem Toxic 1996;34:313–6.
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The information presented in Healthnotes is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over-the-counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2005.